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Curbing Carbs for Diabetes Control

Curbing Carbs for Diabetes Control

As carbs are the major influence in type 2 diabetes, this post deals entirely with type 2 diabetes.health-care-diabetes-info-text-23318754

Diabetes is due to either the pancreas not producing enough insulin or the cells of the body not responding properly to the insulin produced.[5] There are three main types of diabetes mellitus:

  • Type 1 DM results from the pancreas’s failure to produce enough insulin. This form was previously referred to as “insulin-dependent diabetes mellitus” (IDDM) or “juvenile diabetes”. The cause is unknown.[3]It’s thought that glucose may trigger an auto-immune response that tells the pancreas to not produce insulin, but this was only theory when I last checked.
  • Type 2 DM begins with insulin resistance, a condition in which cells fail to respond to insulin properly.[3] As the disease progresses a lack of insulin may also develop.[6] This form was previously referred to as “non insulin-dependent diabetes mellitus” (NIDDM) or “adult-onset diabetes”. The primary cause is excessive body weight and not enough exercise.[3]
  • Gestational diabetes is the third main form and occurs when pregnant women without a previous history of diabetes develop high blood-sugar levels.[3]

Only because of the extra glucose in the blood stream, is type 2 diabetes called diabetes called diabetes. In all actuality,  is the result of carbohydrate overload, and should be called carbolism. I call it carbolism, simply because of its addictive nature, and how it acts upon the body in the same that alcohol does. Alcohol is, after all, a carbohydrate. As this post is only concerned with type 2 diabetes, gestational diabetes isn’t even looked at in this article.

As described on the Carbs, The Newly Found Death Sentence;

  • Diabetic Lancet Device In Hand Stock Photo
    Is Diabetes Your Goal?

    Type 2 diabetes is caused primarily by carrying extra fat on the body and carbs play a major part in that. Carbs cause diabetes because of their need for insulin to be turned into fat so the body can use it. This is the beginning of a downhill spiral that forces the body to make adjustments that it would never have to do, if it were on a diet of protein and fats instead of carbohydrates. Because carbs have to be broken down to their most basic sugar, glucose to be used as a fuel, the glucose flows through your blood stream before it can be metabolized on a cellular level, to be used for that fuel. Glucose needs insulin, to be turned into fat to be digested, to use for energy. Glucose cannot enter the cell without insulin to turn it into fat. The problem is, most of the glucose, after it gets turned into fat, it gets stored as fat in any one of the multitude of fat cells on your body. This takes place in the visceral fat (fat around the internal organs) first and foremost, where it’s the most dangerous. The more carbs you eat, the more insulin your body needs to metabolize those carbs and with a body full of sugar (carbs), you need a lot of insulin to turn all those sugars into fat. After processing a diet full of high carbohydrate food over your lifetime, your body starts to have problems, manufacturing enough insulin, so you can continue to digest the carbs you continue to eat. Because your insulin production can’t keep up with your carb intake, the sugar doesn’t get turned into fat and stays in your blood stream as sugar. It begins to build up in your blood system and you become diabetic. Hence the name insulin dependent diabetes or type two diabetes. Remove the carbs, remove the excess blood glucose. If you remove the glucose from the equation, you remove the diabetes. If you take away the carbs, you take away the obesity and excess glucose. Can it really be that simple? Duh!

Insulin induces HMG-CoA reductase activity, whereas glucagon diminishes HMG-CoA reductase activity.[42] While glucagon production is stimulated by dietary protein ingestion, insulin production is stimulated by dietary carbohydrate ingestion. The rise of insulin is, in general, determined by the digestion of carbohydrates into glucose and subsequent increase in serum glucose levels. In non-diabetics, glucagon levels are very low when insulin levels are high; however, those who have become diabetic no longer suppress glucagon output after eating.”

I would have used a better choice of words, when describing “the digestion of carbohydrates into glucose”, I would have said, “breakdown of carbohydrates into glucose”, as the glucose at this point isn’t digested. It’s just broken down. It doesn’t get digested. Not until it can find a little hormone known as insulin, can it get digested. If it can’t find any insulin, it continues to float around in your blood stream as glucose, looking for something to attach to.

This is why this disorder is called type 2 diabetes and it has little to do with type 1 diabetes except that it allows glucose to continue to flow in you blood with being turned into fat  Type 1 diabetes is an auto-immune disease that shuts down the manufacture of insulin by the pancreas by destroying the cells where insulin is produced.

The fact that carbs are the major cause of type 2 diabetes, should be a warning to all who continue to eat this food. But what should alarm everyone, is what the excess glucose does, that carbs put into your system, because it’s this excess glucose that’s so deadly.

Glucose and cholesterol are the basic building blocks of plaque buildup in your system and it’s this plaque, that kills.

Cholesterol is formed by lipids (fat) clinging  around protein cells called apolipoproteins. They come basically in two forms that make up high density and low density particles, the foundation of cholesterol in your blood. You can read about that on the page about The Foundation of LDL Cholesterol; apolipoprotein B.

It’s excess fat in our bodies that form excess cholesterol in our bodies by providing the fat to be formed into cholesterol, and it’s this excess cholesterol in the form of LDL particles that drives fuel necessary to manifest any one of a multitude of illnesses, disorders, and diseases.

When you combine these two destructive forces of glucose and fat in the body, it’s like two weather systems colliding. Havoc ensues. 

Plaque is by far the worst manifestation of diabetes and a carbohydrate diet. It happens when glucose molecules combine with fat, cholesterol or protein molecules, before they can be utilized by your cells, and displays the true destructive force of glucose on your body.

According to Wikipedia, there are seven different kinds of plaque, AmyloidAtheromaDental plaqueMucoid plaquePleural plaqueSenile plaquesViral plaque. We’re going to look at only 4 of these though.

By far the worst of the plaques caused by digesting wheat and gluten is amyloid plaque, because of all the diseases it has a role in. According to Wikipedia;

  1. Amyloids are insoluble fibrous protein aggregates sharing specific structural traits. They are insoluble and arise from at least 18 inappropriately folded versions of proteins and polypeptides present naturally in the body.[1] These misfolded structures alter their proper configuration such that they erroneously interact with one another or other cell components forming insoluble fibrils. They have been associated with the pathology of more than 20 serious human diseases in that abnormal accumulation of amyloid fibrils in organs may lead to amyloidosis, and may play a role in various neurodegenerative disorders.[2]” The list of diseases caused by amyloid plaque is quite extensive, ranging from Alzheimer’s disease to Diabetes, Parkinson’s and Huntington’s diseases and more. the list on Wikipedia is 21 diseases and disorders or conditions associated with amyloid plaque. In my opinion, amyloid plaque is caused by the digestion of gluten from any source, whether it be wheat, barley or rye. Wikipedia says; “Studies have shown that amyloid deposition is associated with mitochondrial dysfunction and a resulting generation of reactive oxygen species (ROS), which can initiate a signalling pathway leading to apoptosis.[46]” In short amyloid plaque is caused by oxidative stress and cell death, both of which are caused by consumption of gluten and other high starch foods.
  2. Atheromatous Plaques are basically plaques from fats and is the type of plaque that clogs up your artery walls. This is the type of plaque that causes atherosclerosis and leads to heart and cardio vascular disease.
  3. Dental plaque is caused by the excessive amount of sugar on the teeth, creating bacteria, causing decay. (Remember, carbs = sugar.)
  4. Senile plaques (also known as neuritic plaques, senile druse and brain druse) are extracellular deposits of amyloid beta in the grey matter of the brain.[1][2]” 

They cause Alzheimer’s disease and dementia, and play a role in most every other cognitive disorder due to the way this plaque gums of the neurons in your brain.

This is why Type 3 diabetes is considered dementia or brain damage and this is the major reason you don’t want to play around with type 2 diabetes, the next step is loss of your senses, and you won’t even know it, as you won’t realize it as it happens.

Sugar and fat are what cause the plaque buildup

You need both glucose and lipids flowing through your body to create plaque. The glucose attaches itself to a lipid (fat) molecule that has yet to be utilized for energy, and glycates that lipid molecule. The lipids in this case are LDL cholesterol. Low density lipoproteins particles.

Because they float around in such loose form, they’re easily attacked by any free flowing glucose in the system. This is the doom of maintaining  a high amount of glucose in the body.

This is the beginning of plaque. Multiply this by the amount of carbohydrates your ingest everyday. The result is exponentially worse than you would ever want to believe.

So, how do you stop the diabetes? It’s actually a simple decision, stop eating foods that contain wheat. The problem is that following through on this decision, is it’s the hardest thing you’ll ever have to achieve. The biggest problem is that the worse your addiction is, the harder it is to break the addiction, but also, the more important it is to break the addiction. This could be the worst concern with carbohydrate addiction, there are different degrees of addiction, unlike that of heroin, cocaine and alcohol. This problem manifests itself when trying to cut back as the greater your addiction is, the harder it will be to eliminate this food from your diet. But, it’s essential that you eliminate it, because if you don’t, the world of hurt described on Carbs, The Newly Found Death Sentence, will follow you until you either die or quit eating that which causes it.

The easiest path to this goal is explained at Carbs, How To Cut Back.

The Payoff of Life Without Carbs.

The Payoff of Life Without Carbs.

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How often have you ever felt like you just couldn’t control yourself? How many times have you ever felt like someone or something  else was pulling your strings? How often have you ever felt like your emotions and decisions were under the control of someone or something else? How comfortable did it make you feel? You knew you shouldn’t be feeling this way, but you just couldn’t help it. It’s like you’re almost you were being forced to do something you know that you shouldn’t be doing.
hormones-influencing-moods-behavior-34340251You’re not alone. This happens to almost everybody (except for those on a low carbohydrate diet). It’s the nature of addiction. When this happens, that’s your hormones talking to you. Your hormones are the governing agents in your body. Beside dictating almost every function in your body, they dictate when you’re hungry and when your not. They also dictate how much to eat and when to stop. Being a high carbohydrate diet turns control of your hormones over to the food you’re eating instead of keeping it under your control.

time-to-think-creative-brain-idea-concept-background-flat-design-perfect-poster-flyer-presentation-brochure-vector-45489158This is the biggest benefit of living a life without carbs’ influence on your body. It begins to manifest itself when hormones come back under your control and not that of your high carbohydrate diet.
Once carbs are out of the equation, and no longer influencing your hunger hormones (Leptin and Ghrelin), that leaves the door open, for you to control your own hormones and thereby control how these hormones work within your body. The two most important hormones, as far as hunger and your body mass are concerned, are Leptin and Ghrelin.

hormones-list-ghrh-papers-tablet-words-growth-hormone-releasing-hormone-medical-concept-55856070Leptin and Ghrelin are the two hormones that regulate your digestive system, by telling you when you’re hungry and when you’re not, so that’s what we’re going to look at in this post.

According to Nora T. Gedgaudas, an acclaimed nutritional therapist, “Leptin essentially controls mammalian metabolism.”Leptin decides whether to make us hungry and store more fat or to burn fat. When your stomach is full, fat cells release leptin to tell your brain to stop eating. This is your body’s brake for the fork to mouth syndrome. Dr Perlmutter goes on to say in Grain Brain that “millions of Americans qualify as bona fide members of the leptin-resistant club. It’s practically a given if you’ve been eating a high carb diet and don’t sleep well. A few of the signs of leptin resistance; being overweight, unable to lose weight and keep it off, constantly craving comfort foods, fatigue after meals, feeling hungry all the time or at odd hours of the night, desire to snack right after a meal, problems sleeping to name a few. For the complete list, read Grain Brain. Leptin resistance is not a condition to strive for. Its leptin resistance that leads to overeating and it’s a very common condition while on a high carbohydrate diet.

Leptin is the hormone that tells you when to stop eating. It’s called the satiety hormone, but that’s not what’s interesting about Leptin. What’s interesting about Leptin is that it’s created  by your body fat. That means, the more body fat you have, the more Leptin you’ll have. The more Leptin you have, the more resistant to it’s charm you become, meaning that you become Leptin resistant. This means that you eat more food because your hunger takes longer to satiate. This in turn will turn you insulin resistant and that, you don’t want. That’s type two diabetes and it’s bad news.

According to Wikipedia; “Although leptin reduces appetite as a circulating signal, obese individuals generally exhibit a higher circulating concentration of leptin than normal weight individuals due to their higher percentage body fat.[9] These people show resistance to leptin, similar to resistance of insulin in type 2 diabetes, with the elevated levels failing to control hunger and modulate their weight. “

It’s this Leptin resistance that gives control of your hormones over to the foods your eat most, high carbohydrate wheat and grains.

It’s this cycle of carb-fat-hormone control that causes obesity, diabetes and the myriad of other illnesses and diseases that come this high carb diet.  It starts with the plaque that the combination of glucoses and fat , cholesterol and protein have when they combine in your blood stream. There are several kinds of plaque that all have damaging effects on the body and it starts with excess glucose in your blood.

It’s this cycle also, that contributes more than anything else, to a smaller brain, Studies have shown that obese people have smaller brains than normal weight people. These studies have also shown that the fatter you are, the smaller your brain is likelier to be.

Although that doesn’t, in itself, explain why your brain shrinks when you’re fat. How you metabolize carbs explains how that  happens along with the effect of the excess sugar in your blood stream. When sugar meets fat, cholesterol and protein in the blood stream, the sugar glycates the fat, cholesterol and proteins in your blood, turning them into plaques. It’s these plaques that gums up your arteries as well as your brain, therein shrinking its capabilities. On top of that, the gliadin that’s in the gluten, that’s in many grains, has the capability of causing brain damage itself, by forcing your body to create anti-gliadin antibodies, which in turn can attach themselves to purkinje cells in your cerebellum enabling that cell useless, which is then discarded by the brain. Hence, brain damage and smaller brain from eating wheat and grain based products.

Dr William Davis in Wheat Belly, says: “The antigliadin antibodies triggered by gluten can bind to Purkinje cells of the brain, cells unique to the cerebellum. Brain tissue such as Purkinje cells do not have the capacity to regenerate: Once damaged, cerebellar Purkinje cells are gone . . . forever.

Ghrelin, on the other hand, is the hormone that signals your brain that you’re hungry. According to Dr Perlmutter, Ghrelin is the yin to leptin’s yang. This hormone is secreted by the stomach when it’s empty and increases your appetite. As much as leptin tells you to stop eating, Ghrelin is the one that tells your, brain it’s time to eat.

Ghrelin is first and foremost a growth hormone, as well as a hunger hormone, but it also serves many other functions. These functions include, but are certainly not limited to, the following attributes (according to Wikipedia);

  • “Ghrelin promotes intestinal cell proliferation and inhibits apoptosis during inflammatory states and oxidative stress.[49][50] It also suppresses pro-inflammatory mechanisms and augments anti-inflammatory mechanisms, thus creating a possibility of its therapeutic use in various gastrointestinal inflammatory conditions, including colitis, ischemia reperfusion injury, and sepsis.[51][52] Animal models of colitis, ischemia reperfusion, and sepsis-related gut dysfunction have been shown to benefit from therapeutic doses of ghrelin.[51][52] It has also been shown to have regenerative capacity and is beneficial in mucosal injury to the stomach.[53]
  • “The hippocampus plays a significant role in neurotrophy: the cognitive adaptation to changing environments and the process of learning[58][59] and it is a potent stimulator of growth hormone.[11] Animal models indicate that ghrelin may enter the hippocampus from the bloodstream, altering nerve-cell connections, and so altering learning and memory. It is suggested that learning may be best during the day and when the stomach is empty, since ghrelin levels are higher at these times. A similar effect on human memory performance is possible.[58]
  • “Although the vast majority of neurons in the mammalian brain are formed prenatally, parts of the adult brain (for example, the hippocampus) retain the ability to grow new neurons from neural stem cells,[citation needed] a process known as neurogenesis. Neurotrophins are chemicals that help to stimulate and control neurogenesis.”

Looking at the attributes above, Ghrelin not only supports anti-inflammatory mechanisms, but it’s this last attribute that sets it apart from all the other benefits that this diet provides, as it promotes neurotrophins in the brain which in turn help the brain to produce new cells. In other words it makes the brain grow. That means that going hungry turns on factors in your brain that actually make it grow. BDNF is just one of these neurotrophins that I talk about on the MY Life Without Carbs page. There are a few others you can find out about at the previous link.

hormones-list-ghrh-papers-tablet-words-growth-hormone-releasing-hormone-medical-concept-55856070So Ghrelin not only tells when to eat, it also inhibits cell death, it helps control pain and disease by controlling anti-inflammatory mechanisms as well as encouraging our brain to grow by encouraging neurogenesis, the growth of new brain cells. It’s this one factor that intrigues me the most. This means that I can grow new brain cells, something that I thought was lost 30 years ago after my severe closed head injury. I didn’t used to think that brain cells couldn’t grow back, when in all actuality, they’re growing all the time, through neurogenesis, (at least for those who want them to grow).

The question, therein lies, how do we encourage this neurogenesis? I hinted to that in the previous paragraphs and Ghrelin plays an important role in it. But something else just as important, influences brain growth, and that’s exercise.

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Our ancestors ran for their food in primitive times as well as ran for their lives. It was this action (exercise) that allowed our brains to grow as large as they dud. We could not only run hungry, we could run longer and harder because of the diet we were on, as a species at that time (carbs weren’t part of our diet at then). But they are now. What’s worse? They’re in our diet in abundance. And what’s even, worser yet, is that we live a sedentary life style, and it’s this life style coupled with an insatiable appetite for high carbohydrate foods that’s causing this obesity epidemic as well as diabetes epidemic, cancer epidemic, gastro-intestinal epidemic, heart disease epidemic, and that of all of the other diseases that go with it. This to me is the most ablolute worst thing that this food is doing to our society, it’s making us dumber.

High carbohydrate diet + sedentary life style = obesity, smaller
brain, disease and death.gallery-thumbnails

Low carb diet + exercise = longer life, bigger, smarter brain and better immunity to fight off illness and disease.

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This one attribute, in my estimation, is the most important attribute of eating a low carb diet. Dr Perlmutter puts it this way, the fatter you are the smaller your brain. And what we’ve just looked at proves that. It also proves that the thinner you are the larger your brain is likely to be.

To me, that says, those who can’t break their addiction to the carbohydrate curse, are destined to be dumber than those who can break this addiction. The writing of this entire blog in the last three weeks, has proven this fact to me, that it is possible to expand our brains as well as the capabilities of our brains. Thank you Dr. Perlmutter for helping me to realize and understand this. And with this blog, compared to the length of time it took me to write my short bio, I think I’ve proven that.

Studies have shown that calorie restriction in the elderly has improved their memories, as evidenced by this study; A. V. Witte, et al., “Caloric Restriction Improves Memory in Elderly Humans,” Proceedings of the National Academy of Sciences 106, no. 4 (January 27, 2009): 1255–60, The gene that turns on BDNF is activated by a variety of lifestyle habits, including physical exercise, caloric restriction, following a ketogenic diet, and the addition of certain nutrients like curcumin and the omega-3 fat DHA. According to Dr Perlmutter, exercise as well as calorie restriction creates BDNF (Brain Derived Neurotrophic Factor). BDNF is a protein that actually builds new neurons in your brain and makes them work together, by setting them up in neuro networks. It also works well protecting existing neurons, as evidence by the study above. It’s more influential in building your brain, than anything else and it’s difficult for an obese person to manufacture.

This is what Dr Perlmutter talks about, when he mentions that you can control this neurogenesis (brain growth),  He explains in his book Grain Brain;

“The process, as one might expect, is controlled by our DNA. Specifically, a gene located on chromosome 11 codes for the production of a protein called “brain-derived neurotrophic factor,” or BDNF. BDNF plays a key role in creating new neurons. But beyond its role in neurogenesis, BDNF protects existing neurons, ensuring their survivability while encouraging synapse formation, the connection of one neuron to another—a process vital for thinking, learning, and higher levels of brain function. Studies have demonstrated decreased levels of BDNF in Alzheimer’s patients, which, based on an understanding of how BDNF works, should not come as a surprise.  What is perhaps more surprising is the association of BDNF with a variety of neurological conditions, including epilepsy, anorexia nervosa, depression, schizophrenia, and obsessive-compulsive disorder. We now have a firm understanding of the factors that influence our DNA to produce BDNF. And fortunately, these factors are mostly under our direct control. The gene that turns on BDNF is activated by a variety of lifestyle habits, including physical exercise, caloric restriction, following a ketogenic diet, and the addition of certain nutrients like curcumin and the omega-3 fat DHA.”

This is where it really gets good. You begin to experience the full effect of what exercise, combined with calorie restriction and a ketogenic diet, can do for you.

You get a fully charged immune system that keeps you healthy, wealthy and disease free.

Dr Perlmutter goes on to say in Grain Brain;

“Fortunately, and as one would expect, human physiology has developed its own biochemistry to create more protective antioxidants during times of high oxidative stress. Far from being entirely dependent on external food sources of antioxidants, our cells have their own innate ability to generate antioxidant enzymes on demand. High levels of free radicals turn on a specific protein in the nucleus called Nrf2, which essentially opens the door for the production of a vast array of not only our body’s most important antioxidants, but also detoxification enzymes. So if excessive free radicals induce better antioxidant production through this pathway, then the next obvious question is, what else activates Nrf2?”

“Now this is where the story gets really exciting. New research has identified a variety of modifiable factors that can turn on the Nrf2 switch, activating genes that can produce powerful antioxidants and detoxification enzymes. Vanderbilt University’s Dr. Ling Gao has found that when the omega-3 fats EPA and DHA are oxidized, they significantly activate the Nrf2 pathway. For years researchers have noted decreased levels of free radical damage in individuals who consume fish oil (the source of EPA and DHA), but with this new research, the relationship between fish oil and antioxidant protection is now clear. As Dr. Gao reported, “Our data support the hypothesis that the formation of… compounds generated from oxidation of EPA and DHA in vivo can reach concentrations high enough to induce Nrf2-based antioxidant and… detoxification defense systems.” “Not surprisingly, calorie restriction also has been demonstrated in a variety of laboratory models to induce Nrf2 activation”.

“Several natural compounds that turn on antioxidant and detoxification pathways through activation of the Nrf2 system have been identified. Among these are curcumin from turmeric, green tea extract, silymarin (milk thistle), bacopa extract, DHA, sulforaphane (contained in broccoli), and ashwagandha. Each of these substances is effective in turning on the body’s innate production of key antioxidants, including glutathione. And if none of these compounds sounds like something you’re used to having daily in your diet, then you’ll be happy to know that coffee is one of the most powerful Nrf2 activators in nature. Several molecules in coffee, some of which are partly present in the raw material while others are generated during the roasting process, are responsible for this positive effect.”

” Aside from antioxidant function, activation of the Nrf2 pathway turns on the genes to produce a vast array of protective chemicals that further support the body’s detoxification pathways while dampening inflammation—all good things for brain health.”

When calories are reduced in the diets of laboratory animals, they not only live longer (likely as a result of increased antioxidant protection), but also become remarkably resistant to the development of several cancers.”

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We all know that exercise is good for you, but did you know before today that it helps to grow your brain cells? What you probably didn’t know, was that, hunger can produce similar results in helping your brain to generate new brain cells. This to me is what’s so exiting. Just by going hungry, I’m encouraging my brain to generate new brain cells, as well as encouraging my body to easier fight illness and disease by boosting my immune system, by boosting my anti-oxidants exponentially. WOW! How good can this be? All I have to do is to stop eating the foods that cause this kind of behavior in my body,

  1. go hungry once in a while
  2. exercise
  3. eat  ketogenic diet with “certain nutrients like coconut oil, circumin and the omega-3 fat DHA”

and I can be rid of the worry of most everything listed in my first post, Carbs, The Newly Discovered Death Sentence.

If that’s not good news, I don’t know what is.